Dietary Supplement. No. 1 doctor & pharmacist recommended brand (Based on the results of the National Disease and Therapeutic Index syndicated report among physicians who recommend a branded Glucosamine/Chondroitin or Glucosamine supplement, December 2009, and the results of the Pharmacy Times Survey among pharmacists who recommend a bone/joint strengthener dietary supplement, 2010). Shows improvement in joint comfort within 7 days (This statement is based on two human studies of 5-Loxin Advanced using subjective measures in which participants rate their joint health. In these studies, after 7 days, improvement continued to be seen, including in biomarker analysis). 50 - 3 per day softgels. The natural aging process can add excessive stress on your joints. Annoying flare-ups can strike at any time. Now there's a different choice to support healthy joints. The First Choice in Premium Joint Care: Osteo Bi-Flex Double Strength Rapid Release Liquid Softgels are a revolutionary formula that contains glucosamine, chondroitin and MSM as well as the unique international patent pending ingredient 5-Loxin Advanced. Taking 5-Loxin Advanced shows improvement in joint comfort within 7 days. 5-Loxin Advanced, glucosamine and the proprietary blend Joint Shield form a dynamic combo to help: promote mobility; renew cartilage; maintain healthy connective tissue. Osteo Bi-Flex Double Strength Rapid Release Liquid Softgels help protect cartilage and help with annoying flare-ups while helping to renew the cellular components within joints. The only leading brand with Joint Shield, featuring 5-Loxin Advanced. 5-Loxin Advanced is a highly potent concentrated extract of the active ingredient akba from the herb boswellia serrata. 5-Loxin Advanced contains high concentrations of akba, which is an important boswellic acid for helping with joint flare-ups. Osteo Bi-Flex Double Strength Rapid Release Liquid Softgels are a potent, synergistic combination of highly effective ingredients in joint care science and the only leading brand containing Joint Shield. Osteo Bi-Flex is manufactured under the highest standard for product quality, including purity and potency. (These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.)